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Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents.

Song CaiAubin MoutalJie YuLindsey A ChewJoerg IsenseeReena ChawlaKimberly GomezShizhen LuoYuan ZhouAude ChefdevilleCynthia L MaduraSamantha Perez-MillerShreya Sai BellampalliAngie DorameDavid D ScottLiberty François-MoutalZhiming ShanTaylor WoodwardVijay GokhaleAndrea G HohmannTodd W VanderahMarcel PatekMay KhannaTim HuchoRajesh Khanna
Published in: Science translational medicine (2021)
[Figure: see text].
Keyphrases
  • chronic pain
  • pain management
  • neuropathic pain
  • cancer therapy
  • smoking cessation
  • spinal cord injury
  • postoperative pain