Rajesh Khanna

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 84

Top Venues

Pain

Channels (Austin, Tex.)

ACS chemical neuroscience

bioRxiv : the preprint server for biology

University of Arizona

University of Toronto (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Arizona Jan 05 2014

United States

Professor :: Pharmacology

Indiana University School of Medicine Sep 05 2007 - Dec 31 2013

United States

Assistant Professor :: Pharmacology and Toxicology

Toronto Western Research Institute

Canada

Associate Research Scientist :: Division of Genetics & Development

University of California Los Angeles

United States

NSERC Postdoctoral Scholar :: Physiology

Education History

University of Toronto

Canada

PHD :: Physiology

University of Toronto

Canada

MSC :: Toxicology

Publications

Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry (2024)
Donghui Ma, Paz Duran, Reem Al-Ahmad, Sara Hestehave, Margarita Joa, Omar Alsbiei, Erick J Rodríguez-Palma, Yanrong Li, Shilin Wang, Rajesh Khanna, Mingji Dai
C-H Functionalization-Enabled 11-Step Semisynthesis of (-)-Veragranine A and Characterization of Synthetic Analogs in Osteoarthritis-related Pain Treatment. Journal of the American Chemical Society (2024)
Donghui Ma, Paz Duran, Reem Al-Ahmad, Sara Hestehave, Margarita Joa, Omar Alsbiei, Erick J Rodríguez-Palma, Yanrong Li, Shilin Wang, Rajesh Khanna, Mingji Dai
C-H Functionalization-Enabled 11-Step Semisynthesis of (-)-Veragranine A and Characterization of Synthetic Analogs in Osteoarthritis-related Pain Treatment. Journal of the American Chemical Society (2024)
Aleida Jeannette Flores-Pérez, Santiago Loya-López, Arturo Ávalos-Fuentes, Aida Calderon-Rivera, Elisa Damo, Fernando Lazcano-Pérez, Rajesh Khanna, Benjamin Florán-Garduño, Judith Sánchez-Rodríguez
Effect of Crude Extract from the Sea Anemone Bunodeopsis globulifera on Voltage-Gated Ion Channels from Central and Peripheral Murine Nervous Systems. Pharmaceuticals (Basel, Switzerland) 17 (8) (2024)
Heather N Allen, Sara Hestehave, Paz Duran, Tyler S Nelson, Rajesh Khanna
Uncoupling the CRMP2-Ca V 2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model. bioRxiv : the preprint server for biology (2024)
Heather N Allen, Sara Hestehave, Paz Duran, Tyler S Nelson, Rajesh Khanna
Uncoupling the CRMP2-Ca V 2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model. bioRxiv : the preprint server for biology (2024)
Cheng Tang, Paz Duran, Aida Calderon-Rivera, Santiago I Loya-Lopez, Kimberly Gomez, Samantha Perez-Miller, Rajesh Khanna
Regulating neuronal excitability: The role of S -palmitoylation in Na V 1.7 activity and voltage sensitivity. PNAS nexus 3 (6) (2024)
Cheng Tang, Paz Duran, Aida Calderon-Rivera, Santiago I Loya-Lopez, Kimberly Gomez, Samantha Perez-Miller, Rajesh Khanna
Regulating neuronal excitability: The role of S -palmitoylation in Na V 1.7 activity and voltage sensitivity. PNAS nexus 3 (6) (2024)
Vicki J Swier, Katherine A White, Pedro L Negrão de Assis, Tyler B Johnson, Hannah G Leppert, Mitchell J Rechtzigel, David K Meyerholz, Rebecca D Dodd, Dawn E Quelle, Rajesh Khanna, Christopher S Rogers, Jill M Weimer
NF1 +/ex42del miniswine model the cellular disruptions and behavioral presentations of NF1-associated cognitive and motor impairment. Clinical and translational science 17 (6) (2024)
Aleida Jeannette Flores-Pérez, Santiago Loya-López, Arturo Ávalos-Fuentes, Aida Calderon-Rivera, Elisa Damo, Fernando Lazcano-Pérez, Rajesh Khanna, Benjamin Florán-Garduño, Judith Sánchez-Rodríguez
Effect of Crude Extract from the Sea Anemone Bunodeopsis globulifera on Voltage-Gated Ion Channels from Central and Peripheral Murine Nervous Systems. Pharmaceuticals (Basel, Switzerland) 17 (8) (2024)
Tyler S Nelson, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez, Santiago Loya-Lopez, Rajesh Khanna
Mouse models of non-dystrophic and dystrophic myotonia exhibit nociplastic pain-like behaviors. bioRxiv : the preprint server for biology (2024)
Tyler S Nelson, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez, Santiago Loya-Lopez, Rajesh Khanna
Mouse models of non-dystrophic and dystrophic myotonia exhibit nociplastic pain-like behaviors. bioRxiv : the preprint server for biology (2024)
Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry 63 (3) (2024)
Heather N Allen, Sara Hestehave, Paz Duran, Tyler S Nelson, Rajesh Khanna
Uncoupling the CRMP2-Ca V 2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model. bioRxiv : the preprint server for biology (2024)
Aida Calderon-Rivera, Kimberly Gomez, Erick J Rodríguez-Palma, Rajesh Khanna
SUMOylation and DeSUMOylation: Tug of War of Pain Signaling. Molecular neurobiology (2024)
Samantha Perez-Miller, Kimberly Gomez, Rajesh Khanna
Peptide and Peptidomimetic Inhibitors Targeting the Interaction of Collapsin Response Mediator Protein 2 with the N-Type Calcium Channel for Pain Relief. ACS pharmacology & translational science 7 (7) (2024)
Samantha Perez-Miller, Kimberly Gomez, Rajesh Khanna
Peptide and Peptidomimetic Inhibitors Targeting the Interaction of Collapsin Response Mediator Protein 2 with the N-Type Calcium Channel for Pain Relief. ACS pharmacology & translational science 7 (7) (2024)
Cheng Tang, Paz Duran, Aida Calderon-Rivera, Santiago I Loya-Lopez, Kimberly Gomez, Samantha Perez-Miller, Rajesh Khanna
Regulating neuronal excitability: The role of S -palmitoylation in Na V 1.7 activity and voltage sensitivity. PNAS nexus 3 (6) (2024)
Donghui Ma, Paz Duran, Reem Al-Ahmad, Sara Hestehave, Margarita Joa, Omar Alsbiei, Erick J Rodríguez-Palma, Yanrong Li, Shilin Wang, Rajesh Khanna, Mingji Dai
C-H Functionalization-Enabled 11-Step Semisynthesis of (-)-Veragranine A and Characterization of Synthetic Analogs in Osteoarthritis-related Pain Treatment. Journal of the American Chemical Society (2024)
Sara Hestehave, Heather N Allen, Kimberly Gomez, Paz Duran, Aida Calderon-Rivera, Santiago I Loya-Lopez, Erick J Rodríguez-Palma, Rajesh Khanna
Small molecule targeting NaV1.7 via inhibition of CRMP2-Ubc9 interaction reduces pain-related outcomes in a rodent osteoarthritic model. Pain (2024)
Donghui Ma, Paz Duran, Reem Al-Ahmad, Sara Hestehave, Margarita Joa, Omar Alsbiei, Erick J Rodríguez-Palma, Yanrong Li, Shilin Wang, Rajesh Khanna, Mingji Dai
C-H Functionalization-Enabled 11-Step Semisynthesis of (-)-Veragranine A and Characterization of Synthetic Analogs in Osteoarthritis-related Pain Treatment. Journal of the American Chemical Society (2024)
Vicki J Swier, Katherine A White, Pedro L Negrão de Assis, Tyler B Johnson, Hannah G Leppert, Mitchell J Rechtzigel, David K Meyerholz, Rebecca D Dodd, Dawn E Quelle, Rajesh Khanna, Christopher S Rogers, Jill M Weimer
NF1 +/ex42del miniswine model the cellular disruptions and behavioral presentations of NF1-associated cognitive and motor impairment. Clinical and translational science 17 (6) (2024)
Erick J Rodríguez-Palma, Saul Huerta de la Cruz, Ana M Islas-Espinoza, Gabriela Castañeda-Corral, Vinicio Granados-Soto, Rajesh Khanna
Nociplastic pain mechanisms and toll-like receptors as promising targets for its management. Pain (2024)
Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry 63 (3) (2024)
Santiago I Loya-Lopez, Heather N Allen, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez, Upasana Kumar, Rory Shields, Rui Zeng, Akshat Dwivedi, Saumya Saurabh, Olga A Korczeniewska, Rajesh Khanna
Intranasal CRMP2-Ubc9 inhibitor regulates NaV1.7 to alleviate trigeminal neuropathic pain. Pain (2023)
Kimberly Gomez, Harrison J Stratton, Paz Duran, Santiago Loya, Cheng Tang, Aida Calderon-Rivera, Liberty François-Moutal, May Khanna, Cynthia L Madura, Shizhen Luo, Bryan McKiver, Edward Choi, Dongzhi Ran, Lisa Boinon, Samantha Perez-Miller, M Imad Damaj, Aubin Moutal, Rajesh Khanna
Identification and targeting of a unique Na V 1.7 domain driving chronic pain. Proceedings of the National Academy of Sciences of the United States of America 120 (32) (2023)
Ga-Yeon Son, Nguyen Huu Tu, María Daniela Santi, Santiago I Loya-Lopez, Guilherme Henrique Souza Bomfim, Manikandan Vinu, Fang Zhou, Ariya Chaloemtoem, Rama Alhariri, Youssef Idaghdour, Rajesh Khanna, Yi Ye, Rodrigo S Lacruz
The Ca 2+ channel ORAI1 is a regulator of oral cancer growth and nociceptive pain. Science signaling 16 (801) (2023)
Kimberly Gomez, Ulises Santiago, Tyler S Nelson, Heather N Allen, Aida Calderon-Rivera, Sara Hestehave, Erick J Rodríguez-Palma, Yuan Zhou, Paz Duran, Santiago Loya-Lopez, Elaine Zhu, Upasana Kumar, Rory Shields, Eda Koseli, Bryan McKiver, Denise Giuvelis, Wanhong Zuo, Kufreobong E Inyang, Angie Dorame, Aude Chefdeville, Dongzhi Ran, Samantha Perez-Miller, Yi Lu, Xia Liu, Handoko Handoko, Paramjit S Arora, Marcel Patek, Aubin Moutal, May Khanna, Huijuan Hu, Geoffroy Laumet, Tamara King, Jing Wang, M Imad Damaj, Olga A Korczeniewska, Carlos Jaime Camacho, Rajesh Khanna
A peptidomimetic modulator of the Ca V 2.2 N-type calcium channel for chronic pain. Proceedings of the National Academy of Sciences of the United States of America 120 (47) (2023)
Kimberly Gomez, Paz Duran, Raquel Tonello, Heather N Allen, Lisa Boinon, Aida Calderon-Rivera, Santiago Loya-López, Tyler S Nelson, Dongzhi Ran, Aubin Moutal, Nigel W Bunnett, Rajesh Khanna
Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors. Pain (2023)
Tatiana Brustovetsky, Rajesh Khanna, Nickolay Brustovetsky
CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. Cells 12 (9) (2023)
Ya-Ming Xu, E M Kithsiri Wijeratne, Aida Calderon-Rivera, Santiago Loya-López, Samantha Perez-Miller, Rajesh Khanna, A A Leslie Gunatilaka
Argentatin C Analogues with Potential Antinociceptive Activity and Other Triterpenoid Constituents from the Aerial Parts of Parthenium incanum . ACS omega 8 (22) (2023)
Tatiana Brustovetsky, Rajesh Khanna, Nickolay Brustovetsky
CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. Cells 12 (9) (2023)
Tatiana Brustovetsky, Rajesh Khanna, Nickolay Brustovetsky
CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. Cells 12 (9) (2023)
Kimberly Gomez, Heather N Allen, Paz Duran, Santiago Loya-Lopez, Aida Calderon-Rivera, Aubin Moutal, Cheng Tang, Tyler S Nelson, Samantha Perez-Miller, Rajesh Khanna
Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain. Pain (2023)
Tatiana Brustovetsky, Rajesh Khanna, Nickolay Brustovetsky
CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. Cells 12 (9) (2023)
Santiago I Loya-Lopez, Heather N Allen, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez, Upasana Kumar, Rory Shields, Rui Zeng, Akshat Dwivedi, Saumya Saurabh, Olga A Korczeniewska, Rajesh Khanna
Intranasal CRMP2-Ubc9 Inhibitor Regulates Na V 1.7 to Alleviate Trigeminal Neuropathic Pain. bioRxiv : the preprint server for biology (2023)
Tam T Quach, Harrison J Stratton, Rajesh Khanna, Sabrina Mackey-Alfonso, Nicolas Deems, Jerome Honnorat, Kathrin Meyer, Anne-Marie Duchemin
Neurodegenerative Diseases: From Dysproteostasis, Altered Calcium Signalosome to Selective Neuronal Vulnerability to AAV-Mediated Gene Therapy. International journal of molecular sciences 23 (22) (2022)
Paz Duran, Rajesh Khanna
Some Like It Hot: Dynamic Control of Cav2.2 Channels By Chili Peppers. Function (Oxford, England) 4 (1) (2022)
Harrison J Stratton, Lisa Boinon, Kimberly Gomez, Laurent Martin, Paz Duran, Dongzhi Ran, Yuan Zhou, Shizhen Luo, Samantha Perez-Miller, Marcel Patek, Mohab M Ibrahim, Amol Patwardhan, Aubin Moutal, Rajesh Khanna
Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain. Pain (2022)
Kimberly Gomez, Cheng Tang, Bin Tan, Samantha Perez-Miller, Dongzhi Ran, Santiago Loya, Aida Calderon-Rivera, Harrison J Stratton, Paz Duran, Kyleigh A Masterson, Anna T Gabrielsen, Omar Alsbiei, Angie Dorame, Maria Serafini, Aubin Moutal, Jun Wang, Rajesh Khanna
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca 2+ Channels and Pain. ACS chemical neuroscience 13 (13) (2022)
Paz Duran, Rajesh Khanna
Some Like It Hot: Dynamic Control of Cav2.2 Channels By Chili Peppers. Function (Oxford, England) 4 (1) (2022)
Kimberly Gomez, Rajesh Khanna
Ca V 3.2 calcium channels: new players in facial pain. Pain 163 (12) (2022)
Aida Calderon-Rivera, Santiago Loya-Lopez, Kimberly Gomez, Rajesh Khanna
Plant and fungi derived analgesic natural products targeting voltage-gated sodium and calcium channels. Channels (Austin, Tex.) 16 (1) (2022)
Lisa Boinon, Jie Yu, Cynthia L Madura, Aude Chefdeville, Douglas L Feinstein, Aubin Moutal, Rajesh Khanna
Conditional knockout of CRMP2 in neurons, but not astrocytes, disrupts spinal nociceptive neurotransmission to control the initiation and maintenance of chronic neuropathic pain. Pain 163 (2) (2022)
Harrison J Stratton, Lisa Boinon, Kimberly Gomez, Laurent Martin, Paz Duran, Dongzhi Ran, Yuan Zhou, Shizhen Luo, Samantha Perez-Miller, Marcel Patek, Mohab M Ibrahim, Amol Patwardhan, Aubin Moutal, Rajesh Khanna
Targeting the VEGF-A/Neuropilin 1 axis for relief of neuropathic pain. Pain (2022)
Jiahe Li, Harrison J Stratton, Sabina A Lorca, Peter M Grace, Rajesh Khanna
Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats. Channels (Austin, Tex.) 16 (1) (2022)
Aleyah E Goins, Kimberly Gomez, Dongzhi Ran, Mitra Afaghpour-Becklund, Rajesh Khanna, Sascha R A Alles
Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain. Pflugers Archiv : European journal of physiology 474 (4) (2022)
Paz Duran, Rajesh Khanna
Some Like It Hot: Dynamic Control of Cav2.2 Channels By Chili Peppers. Function (Oxford, England) 4 (1) (2022)
Tatiana Brustovetsky, Rajesh Khanna, Nickolay Brustovetsky
CRMP2 Is Involved in Regulation of Mitochondrial Morphology and Motility in Neurons. Cells 10 (10) (2021)
Laurent F Martin, Mohab M Ibrahim, Kimberly Gomez, Jie Yu, Song Cai, Lindsey A Chew, Shreya S Bellampalli, Aubin Moutal, Tally Largent-Milnes, Frank Porreca, Rajesh Khanna, Baldomero M Olivera, Amol Patwardhan
Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel (Cav2.3) pathway to mediate spinal antinociception. Pain 163 (9) (2021)
Samantha Perez-Miller, Marcel Patek, Aubin Moutal, Paz Duran, Carly R Cabel, Curtis A Thorne, Samuel K Campos, Rajesh Khanna
Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry. ACS chemical neuroscience 12 (8) (2021)
Kimberly Gomez, Dongzhi Ran, Cynthia L Madura, Aubin Moutal, Rajesh Khanna
Non-SUMOylated CRMP2 decreases NaV1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15. Molecular brain 14 (1) (2021)
Harrison J Stratton, Rajesh Khanna
Sculpting Dendritic Spines during Initiation and Maintenance of Neuropathic Pain. The Journal of neuroscience : the official journal of the Society for Neuroscience 40 (40) (2021)
Dongzhi Ran, Kimberly Gomez, Aubin Moutal, Marcel Patek, Samantha Perez-Miller, Rajesh Khanna
Comparison of quinazoline and benzoylpyrazoline chemotypes targeting the CaVα-β interaction as antagonists of the N-type CaV2.2 channel. Channels (Austin, Tex.) 15 (1) (2021)
Song Cai, Aubin Moutal, Jie Yu, Lindsey A Chew, Joerg Isensee, Reena Chawla, Kimberly Gomez, Shizhen Luo, Yuan Zhou, Aude Chefdeville, Cynthia L Madura, Samantha Perez-Miller, Shreya Sai Bellampalli, Angie Dorame, David D Scott, Liberty François-Moutal, Zhiming Shan, Taylor Woodward, Vijay Gokhale, Andrea G Hohmann, Todd W Vanderah, Marcel Patek, May Khanna, Tim Hucho, Rajesh Khanna
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents. Science translational medicine 13 (619) (2021)
Yanxia Chen, Aubin Moutal, Edita Navratilova, Caroline M Kopruszinski, Xu Yue, Megumi Ikegami, Michele Chow, Iori Kanazawa, Shreya Sai Bellampalli, Jennifer Yanhua Xie, Amol Patwardhan, Kenner Rice, Howard L Fields, Armen Akopian, Volker Neugebauer, David Dodick, Rajesh Khanna, Frank Porreca
The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females. Science translational medicine 12 (529) (2021)
Rajesh Khanna, Aubin Moutal, Samantha Perez-Miller, Aude Chefdeville, Lisa Boinon, Marcel Patek
Druggability of CRMP2 for Neurodegenerative Diseases. ACS chemical neuroscience 11 (17) (2020)
Anthony J Schulien, Chung-Yang Yeh, Bailey N Orange, Olivia J Pav, Madelynn P Hopkins, Aubin Moutal, Rajesh Khanna, Dandan Sun, Jason A Justice, Elias Aizenman
Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischemic stroke in mice by declustering Kv2.1 channels. Science advances 6 (27) (2020)
Aubin Moutal, Yingshi Ji, Shreya Sai Bellampalli, Rajesh Khanna
Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury. Molecular brain 13 (1) (2020)
Samantha Perez-Miller, Marcel Patek, Aubin Moutal, Carly R Cabel, Curtis A Thorne, Samuel K Campos, Rajesh Khanna
In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein. bioRxiv : the preprint server for biology (2020)
Yuan Zhou, Song Cai, Kimberly Gomez, E M Kithsiri Wijeratne, Yingshi Ji, Shreya S Bellampalli, Shizhen Luo, Aubin Moutal, A A Leslie Gunatilaka, Rajesh Khanna
1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain. Molecular brain 13 (1) (2020)
Song Cai, Zhiming Shan, Zhongjun Zhang, Aubin Moutal, Rajesh Khanna
Activity of T-type calcium channels is independent of CRMP2 in sensory neurons. Channels (Austin, Tex.) 13 (1) (2020)
Harrison J Stratton, Rajesh Khanna
Just in time! Identification of a novel mechanism for treating PIPN. The Journal of physiology 598 (12) (2020)
Rebecca F Krall, Aubin Moutal, Matthew B Phillips, Hila Asraf, Jon W Johnson, Rajesh Khanna, Michal Hershfinkel, Elias Aizenman, Thanos Tzounopoulos
Synaptic zinc inhibition of NMDA receptors depends on the association of GluN2A with the zinc transporter ZnT1. Science advances 6 (27) (2020)
Aubin Moutal, Sergey Kalinin, Kathy Kowal, Natalia Marangoni, Jeffrey Dupree, Shao Xia Lin, Kinga Lis, Lucia Lisi, Kenneth Hensley, Rajesh Khanna, Douglas L Feinstein
Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis. ASN neuro 11 (2020)
Aubin Moutal, Zhiming Shan, Victor G Miranda, Liberty François-Moutal, Cynthia L Madura, May Khanna, Rajesh Khanna
Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief. Channels (Austin, Tex.) 13 (1) (2020)
Yuan Zhou, Song Cai, Aubin Moutal, Jie Yu, Kimberly Gómez, Cynthia L Madura, Zhiming Shan, Nancy Y N Pham, Maria J Serafini, Angie Dorame, David D Scott, Liberty François-Moutal, Samantha Perez-Miller, Marcel Patek, May Khanna, Rajesh Khanna
The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels. ACS chemical neuroscience 10 (12) (2019)
Aubin Moutal, Katherine A White, Aude Chefdeville, Rachel N Laufmann, Peter F Vitiello, Douglas Feinstein, Jill M Weimer, Rajesh Khanna
Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions. Molecular neurobiology 56 (10) (2019)
Chung-Yang Yeh, Zhaofeng Ye, Aubin Moutal, Shivani Gaur, Amanda M Henton, Stylianos Kouvaros, Jami L Saloman, Karen A Hartnett-Scott, Thanos Tzounopoulos, Rajesh Khanna, Elias Aizenman, Carlos J Camacho
Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant. Proceedings of the National Academy of Sciences of the United States of America 116 (31) (2019)
Aubin Moutal, Song Cai, Shizhen Luo, Raphaëlle Voisin, Rajesh Khanna
CRMP2 is necessary for Neurofibromatosis type 1 related pain. Channels (Austin, Tex.) 12 (1) (2019)
Yan Jin, Song Cai, Yuepeng Jiang, Kai Zhong, Chengping Wen, Yeping Ruan, Lindsey A Chew, Rajesh Khanna, Zhenghao Xu, Jie Yu
Tetramethylpyrazine Reduces Epileptogenesis Progression in Electrical Kindling Models by Modulating Hippocampal Excitatory Neurotransmission. ACS chemical neuroscience 10 (12) (2019)
Rami Musharrafieh, Jiantao Zhang, Peter Tuohy, Naoya Kitamura, Shreya Sai Bellampalli, Yanmei Hu, Rajesh Khanna, Jun Wang
Discovery of Quinoline Analogues as Potent Antivirals against Enterovirus D68 (EV-D68). Journal of medicinal chemistry 62 (8) (2019)
Zhiming Shan, Song Cai, Jie Yu, Zhongjun Zhang, Tissiana Gabriela Menna Vallecillo, Maria Jin Serafini, Ann Mary Thomas, Nancy Yen Ngan Pham, Shreya Sai Bellampalli, Aubin Moutal, Yuan Zhou, Guo-Bo Xu, Ya-Ming Xu, Shizhen Luo, Marcel Patek, John M Streicher, A A Leslie Gunatilaka, Rajesh Khanna
Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels. ACS chemical neuroscience 10 (6) (2019)
Liberty François-Moutal, Razaz Felemban, David D Scott, Melissa R Sayegh, Victor G Miranda, Samantha Perez-Miller, Rajesh Khanna, Vijay Gokhale, Daniela C Zarnescu, May Khanna
Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS). ACS chemical biology 14 (9) (2019)
Jeffrey Parrilla-Carrero, William C Buchta, Priyodarshan Goswamee, Oliver Culver, Greer McKendrick, Benjamin Harlan, Aubin Moutal, Rachel Penrod, Abigail Lauer, Viswanathan Ramakrishnan, Rajesh Khanna, Peter W Kalivas, Arthur C Riegel
Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (17) (2018)
Liberty François-Moutal, David Donald Scott, Samantha Perez-Miller, Vijay Gokhale, May Khanna, Rajesh Khanna
Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels. Channels (Austin, Tex.) 12 (1) (2018)
Jie Yu, Aubin Moutal, Angie Dorame, Shreya S Bellampalli, Aude Chefdeville, Iori Kanazawa, Nancy Y N Pham, Ki Duk Park, Jill M Weimer, Rajesh Khanna
Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission. Molecular neurobiology 56 (7) (2018)
Song Cai, Shreya S Bellampalli, Jie Yu, Wennan Li, Yingshi Ji, E M Kithsiri Wijeratne, Angie Dorame, Shizhen Luo, Zhiming Shan, May Khanna, Aubin Moutal, John M Streicher, A A Leslie Gunatilaka, Rajesh Khanna
(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels. ACS chemical neuroscience 10 (3) (2018)
Sara S Parker, Aubin Moutal, Song Cai, Sambamurthy Chandrasekaran, Mackenzie R Roman, Anita A Koshy, Rajesh Khanna, Konrad E Zinsmaier, Ghassan Mouneimne
High Fidelity Cryopreservation and Recovery of Primary Rodent Cortical Neurons. eNeuro 5 (5) (2018)
Aubin Moutal, Lex Salas Villa, Seul Ki Yeon, Kyle T Householder, Ki Duk Park, Rachael W Sirianni, Rajesh Khanna
CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation. Molecular neurobiology 55 (5) (2017)
Aubin Moutal, Wennan Li, Yue Wang, Weina Ju, Shizhen Luo, Song Cai, Liberty François-Moutal, Samantha Perez-Miller, Jackie Hu, Erik Thomas Dustrude, Todd W Vanderah, Vijay Gokhale, May Khanna, Rajesh Khanna
Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides. British journal of pharmacology 175 (12) (2017)
Chung-Yang Yeh, Ashlyn M Bulas, Aubin Moutal, Jami L Saloman, Karen A Hartnett, Charles T Anderson, Thanos Tzounopoulos, Dandan Sun, Rajesh Khanna, Elias Aizenman
Targeting a Potassium Channel/Syntaxin Interaction Ameliorates Cell Death in Ischemic Stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (23) (2017)
Erik Thomas Dustrude, Samantha Perez-Miller, Liberty François-Moutal, Aubin Moutal, May Khanna, Rajesh Khanna
A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Channels (Austin, Tex.) 11 (4) (2017)
Erik T Dustrude, Aubin Moutal, Xiaofang Yang, Yuying Wang, May Khanna, Rajesh Khanna
Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proceedings of the National Academy of Sciences of the United States of America 113 (52) (2016)
Aubin Moutal, Liberty François-Moutal, Samantha Perez-Miller, Karissa Cottier, Lindsey Anne Chew, Seul Ki Yeon, Jixun Dai, Ki Duk Park, May Khanna, Rajesh Khanna
(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Molecular neurobiology 53 (3) (2015)

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Publication Activity (10 Years)

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Rajesh Khanna