Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs.
Saara MarttilaLeena E ViiriPashupati P MishraBrigitte KühnelPamela R Matias-GarciaLeo-Pekka LyytikäinenTiina CederNina MononenWolfgang RathmannJuliane WinkelmannAnnette PetersMika KähönenNina Hutri-KähönenMarkus JuonalaKatriina Aalto-SetäläOlli RaitakariTerho LehtimäkiMelanie WaldenbergerEmma RaitoharjuPublished in: Clinical epigenetics (2021)
These results indicate that nc886 metastable epiallele methylation is tuned by the periconceptional conditions and it associates with glucose metabolism through the expression of the ncRNAs coded in the epiallele region.