miR-223-3p targets FBXW7 to promote epithelial-mesenchymal transition and metastasis in breast cancer.

Yuli WangShuang ShiYunshan WangXuhua ZhangXiaoyan LiuJuan LiPeilong LiLutao DuChuanxin Wang

Published in: Thoracic cancer (2021)

Our study revealed a physical and functional relationship among miR-223-3p and FBXW7. By negatively regulating FBXW7 expression, miR-223-3p exerts a tumor promotion role promoting cell invasion and metastasis in breast cancer.

Keyphrases

epithelial mesenchymal transition
poor prognosis
physical activity
transforming growth factor
mental health
single cell
breast cancer risk
childhood cancer