Navigating choice in the face of uncertainty: using a theory informed qualitative approach to identifying potential patient barriers and enablers to participating in an early phase chimeric antigen receptor T (CAR-T) cell therapy trial.
Gisell CastilloManoj M LaluSarah AsadMadison FosterNatasha KekreDean A FergussonTerry HawryshHarold AtkinsKednapa ThavornJoshua MontroyStuart SchwartzRobert A HoltRaewyn BroadyJustin PresseauPublished in: BMJ open (2021)
Using the TDF allowed us to identify factors that might undermine participation to a CAR-T cell therapy trial and to optimise recruitment processes by considering patient perspectives to taking part in early phase trials.Trial regestration: NCT03765177; Pre-results.