TREM2 R47H variant and risk for Alzheimer's disease: assessment in a Greek population and updated meta-analysis.

Dimitrios RikosVasileios SiokasAlexios-Fotios A MentisAthina-Maria AloizouIoannis N LiampasZisis TsourisEleni PeristeriPolyxeni StamatiGeorgios M HadjigeorgiouEfthimios Dardiotis

Published in: The International journal of neuroscience (2022)

The rs75932628 was associated with AD in the Greek sample. Our meta-analysis, covering a total population of over 168,000 people, also showed a significant association of the allele with AD in Caucasian populations.

Keyphrases

systematic review
meta analyses
case control
randomized controlled trial
cognitive decline
genetic diversity