Safety and efficacy of S1P receptor modulators for the induction and maintenance phases in inflammatory bowel disease: A systematic review and meta-analysis of randomized controlled trials.

Abdullah AkramMisha AhmedKanza FarhanAreeb OmerShamama KaleemAli Tahir KhanUzma AslamMuhammad Abdullah TahirSaria MemonAyatul KaramHumam FurqanMuhammad Umair AnjumPratik Bhattarai

Published in: Medicine (2024)

S1PrMs show promising potential for establishing histologic remission, endoscopic improvement, clinical remission, and corticosteroid-free clinical remission. With more studies and clinical trials, these modulators may become a reliable therapeutic choice for UC patients everywhere.

Keyphrases

clinical trial
end stage renal disease
disease activity
small molecule
ulcerative colitis
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
systemic lupus erythematosus
randomized controlled trial
decision making
phase ii