High expression of folate receptor alpha is associated with poor prognosis in patients with cervical cancer.

Shu Yazaki Yuki Kojima Hiroshi Yoshida Shigemasa Takamizawa Rui Kitadai Tadaaki Nishikawa Tatsunori Shimoi Kazuki Sudo Ayumi Saito Hitomi Sumiyoshi Okuma Maki Tanioka Emi Noguchi Masaya Uno Mitsuya Ishikawa Tomoyasu Kato Yasuhiro Fujiwara Yuichiro Ohe Kan Yonemori

Published in: Journal of gynecologic oncology (2022)

In cervical cancer, FRα expression was elevated in metastatic tumors and high expression was associated with a worse prognosis. Our study supports the development of FRα-targeted therapy for advanced cervical cancer.

Keyphrases

poor prognosis
long non coding rna
small cell lung cancer
squamous cell carcinoma
binding protein
drug delivery
cancer therapy