In search of a dose-response relationship in SSRIs-a systematic review, meta-analysis, and network meta-analysis.

C BraunA AdamsL RinkT BschorK KuhrChristopher Baethge

Published in: Acta psychiatrica Scandinavica (2020)

There is no conclusive level I or level II evidence of a clinically meaningful dose-response relationship of SSRIs as a group or of single substances. High SSRI doses are not recommended as routine treatment.

Keyphrases

systematic review
meta analyses
case control
randomized controlled trial