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Small nucleolar RNA host gene 18 controls vascular smooth muscle cell contractile phenotype and neointimal hyperplasia.

Kaiyuan NiuChengxin ZhangMei YangEithne Margaret MaguireZhenning ShiShasha SunJianping WuChenxin LiuWeiwei AnXinxin WangShan GaoShenglin GeQingzhong Xiao
Published in: Cardiovascular research (2024)
We demonstrate that SNHG18 is a novel regulator in governing VSMC contractile phenotype and preventing injury-induced neointimal hyperplasia. Our findings have important implications for therapeutic targeting snhg18/miR-22-3p signalling in vascular diseases.
Keyphrases
  • smooth muscle
  • poor prognosis
  • single cell
  • high glucose
  • diabetic rats
  • cell therapy
  • transcription factor
  • copy number
  • cancer therapy
  • drug induced
  • bone marrow
  • nucleic acid
  • angiotensin ii
  • vascular smooth muscle cells