Environmental toxicants and health adversities: A review on interventions of phytochemicals.
Adewale Allen Sokan-AdeagaMicheal Ayodeji Sokan-AdeagaEniola Deborah Sokan-AdeagaAnastasia Nkem OparajiHoseinzadeh EdrisEsther Oluwabukunola TellaFrancis Adeniyi BalogunMuhammad AledehOluwatosin Emmanuel AmubieyaPublished in: Journal of public health research (2023)
Toxicity arising from environmental contaminants has attracted global interest in the last few decades, due to the high morbidity and mortality associated with them. Efforts have been made to combat the consequential outcomes of environmental toxicity in humans through traditional remediation techniques and therapeutic measures which have been hampered by one or more limitations. Consequently, this scenario has triggered interest in the medicinal properties of phytochemicals. Thus, this review gives a succinct and in-depth elucidation of the various environmental contaminants and their toxicity effects on humans. It delves into the various classes of phytochemicals and their intervention roles. The study adopted a desk review of existing literatures from scientific reports and peer reviewed articles through triangulation of data sources. "Phytochemicals" are group of secondary metabolites obtained from plants with medicinal properties. These groups of compounds are included but not limited to flavonoids, tannins, saponins, alkaloids, cardenoloids, terpenoids, and phytosteroids. This review corroborates the prophylactic and therapeutics efficacy of these phytochemicals as anti-metastatic, anti-inflammatory, anti-aging, anti-oxidant, anti-microbial and live saving substances with empirical findings from several laboratory, clinical trials and epidemiologic studies. It conclude that given the wide range of medicinal properties of phytochemicals, there is an urgent need for its full optimization in the pharmaceutical industry and future studies should focus on identifying the bioactive molecules in these compounds and its effectiveness against mixer toxicity.
Keyphrases
- drinking water
- oxidative stress
- human health
- clinical trial
- anti inflammatory
- randomized controlled trial
- healthcare
- life cycle
- public health
- squamous cell carcinoma
- emergency department
- small molecule
- type diabetes
- oxide nanoparticles
- quality improvement
- social media
- ms ms
- metabolic syndrome
- optical coherence tomography
- big data
- case control
- deep learning
- artificial intelligence
- phase ii
- drug discovery