Evaluation of published population pharmacokinetic models to inform tacrolimus dosing in adult heart transplant recipients.
Ranita KirubakaranStefanie HennigBen MaslenRichard Osborne DayJane Ellen CarlandSophie Lena StockerPublished in: British journal of clinical pharmacology (2021)
All models evaluated were unable to adequately describe tacrolimus pharmacokinetics in adult heart transplant recipients included in this study. Further work is required to describe tacrolimus pharmacokinetics for our heart transplant recipient cohort.