Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom.

Ahmed Bayoumy BayoumyElsa L S A van LiereMelek SimsekBen WarnerAathavan LoganayagamJeremy D SandersonSimon AndersonJonathan NolanNanne K de BoerChris J J MulderAzhar Ansari

Published in: BMC gastroenterology (2020)

Long-term follow-up suggests that TG can be an effective and well-tolerated therapy in more than half of difficult-to-treat and multi-therapy failing IBD patients. Findings of this study indicate that TG can be used safely and the occurrence of hepatotoxicity was low. The incidence rate of NRH was within the background incidence.

Keyphrases

end stage renal disease
risk factors
chronic kidney disease
newly diagnosed
emergency department
drug induced
cross sectional
bone marrow
combination therapy
patient reported