Depot medroxyprogesterone acetate and norethisterone enanthate differentially impact T-cell responses and expression of immunosuppressive markers.
Allen T MatubuSharon L HillierLeslie A MeynKevin A StonerFelix MhlangaMike MbizvoAaron MarambaZvavahera M ChirenjeSharon L AchillesPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)
Activation of T-cells in response to ex vivo stimulation is suppressed at steady state DMPA concentration and resolves at nadir concentration, suggesting DMPA immunosuppressive effects may be transient.