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The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders.

Viktoriya S ShramkoYana Vladimirovna PolonskayaElena V KashtanovaEkaterina Mikhailovna StakhnevaYuliya Igorevna Ragino
Published in: Biomolecules (2020)
This review presents existing evidence of the influence of saturated and unsaturated fatty acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most relevant fatty acids, such as myristic (C14:0), palmitic (C16:0), stearic (C18:0), palmitoleic (C16:1), oleic (C18:1), linoleic (C18:2), α-linolenic (C18:3, ω-3), γ-linolenic (C18:3, ω-6), arachidonic (C20:4), eicosapentaenoic (C20:5), docosahexaenoic (C22:6), and docosapentaenoic (C22:5) acid. The accumulated knowledge has expanded the understanding of the involvement of fatty acids in metabolic processes, thereby enabling the transition from basic exploratory studies to practical issues of application of these biomolecules to CVD treatment. In the future, these findings are expected to facilitate the interpretation and prognosis of changes in metabolic lipid aberrations in CVD.
Keyphrases
  • fatty acid
  • cardiovascular disease
  • healthcare
  • copy number
  • gene expression
  • coronary artery disease
  • big data
  • data analysis