Effects of Aged Stored Autologous Red Blood Cells on Human Endothelial Function.
Michael G RisbanoTamir KaniasDarrel TriulziChenell DonadeeSuchitra BargeJessica BadlamShilpa JainAndrea M BelangerDaniel B Kim-ShapiroMark T GladwinPublished in: American journal of respiratory and critical care medicine (2016)
We demonstrate that the transfusion of blood at the limits of Food and Drug Administration-approved storage has a significant effect on the forearm circulation and impairs endothelial function. Clinical trial registered with www.clinicaltrials.gov (NCT 01137656).