Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis.

Anthony J LemboWilliam D CheyLucinda A HarrisRosita FrazierDarren M BrennerLin ChangBrian E LacySusan Edelstein Yang Yang Suling Zhao David P Rosenbaum

Published in: The American journal of gastroenterology (2024)

Tenapanor significantly reduced abdominal symptoms in patients with irritable bowel syndrome with constipation, particularly pain, discomfort, and bloating measured by AS, compared with placebo.

Keyphrases

irritable bowel syndrome
clinical trial
chronic pain
pain management
phase iii
neuropathic pain
double blind
phase ii
sleep quality
randomized controlled trial
spinal cord
spinal cord injury
depressive symptoms