Proinflammatory effects and mechanisms of calprotectin on human gingival fibroblasts.
Hongyu GaoJ HouH MengX ZhangY ZhengL PengPublished in: Journal of periodontal research (2017)
Our findings suggest that calprotectin exerts proinflammatory effects on HGFs via the S100A9 subunit and TLR4-mediated NF-κB and MAPK signaling pathways.
Keyphrases
- signaling pathway
- pi k akt
- endothelial cells
- disease activity
- induced apoptosis
- toll like receptor
- epithelial mesenchymal transition
- oxidative stress
- inflammatory response
- nuclear factor
- induced pluripotent stem cells
- immune response
- pluripotent stem cells
- lps induced
- rheumatoid arthritis
- cell proliferation
- protein kinase