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A new non-dilution rapid desensitization protocol successfully applied to all-grade platinum hypersensitivity.

Soo Jie ChungSung-Yoon KangRae-Young KangYoung-Chan KimKyung-Hun LeeTae-Yong KimSae-Won HanHye-Ryun Kang
Published in: Cancer chemotherapy and pharmacology (2018)
The new non-dilution desensitization protocol was safe and effective for re-administration of culprit platinum agents in patients with a history of HSRs. Therefore, this new protocol can be used as an alternative to existing protocols using multiple serial dilutions.
Keyphrases
  • randomized controlled trial
  • liquid chromatography tandem mass spectrometry
  • liquid chromatography
  • gas chromatography
  • simultaneous determination