Longitudinal clinical trajectory analysis of individuals before and after diagnosis of Type 2 Diabetes Mellitus (T2DM) indicates that vascular problems start early.
Adrian H HealdKai ChangTing JiaHailong SunQiguang ZhengXinyan WangJianan XiaStedman MHelene FachimMartin GibsonXuezhong ZhouSimon George AndersonYonghong PengWilliam OllierPublished in: International journal of clinical practice (2021)
These observations provide an intriguing and novel insight into the onset and natural progression of T2DM. They suggest an early phase of potentially related disease activity well before any clinical diagnosis of diabetes is made. Further studies on a larger cohort of DARE patients are underway to explore the utility of establishing predictive risk scores.
Keyphrases
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- end stage renal disease
- type diabetes
- rheumatoid arthritis patients
- glycemic control
- ankylosing spondylitis
- newly diagnosed
- ejection fraction
- chronic kidney disease
- mental health
- juvenile idiopathic arthritis
- peritoneal dialysis
- skeletal muscle
- metabolic syndrome
- patient reported outcomes
- patient reported
- weight loss
- case control