Potential performance of a 0/1-hour algorithm and a single cut-off measure of high-sensitivity troponin T in a diverse population: Main results of the IN-HOPE study.
Pedro Gabriel Melo de Barros E SilvaAna Amaral FerreiraFelipe MalafaiaAntonielle Figueiredo Macedo Tavares ReisHenry SznejderAugusto Celso De Araujo Lopes JuniorCamila Anacleto AgostinhoLuiz Henrique de Oliveira FonsecaDébora Vieira Donini OkitoiCelso Musa CorreaEduardo ZinconeMarcelo Paiva CuryGustavo Augusto Lopes RosaHenrique Barbosa RibeiroAlexandre de Matos SoeiroCarlos Alexandre Lemes de OliveiraGuilherme Capelli KuusbergLouis Nakayama OheDouglas de Oliveira SouzaAdriana Bertolami ManfrediAmanda Francisco MartinsPedro Paulo Nogueres SampaioThiago Baganha VazLuciana Ferreira FrancoCarlos Eduardo Dos Santos FerreiraRenato Delascio LopesPublished in: European heart journal. Acute cardiovascular care (2023)
In this large multicentre study, a 0/1-h algorithm had the potential to classify as rule in or out almost 80% of the patients. The rule-out protocol had high negative predictive value regardless of clinical risk scores. Categories of levels of hs-cTn T also showed good accuracy in discriminating risk of the patients with a very favourable prognosis for cardiovascular death in the group with values < 5 ng/L.