The Effect of Frailty on the Efficacy and Safety of Intensive Blood Pressure Control: A Post Hoc Analysis of the SPRINT Trial.
Zhiyan WangXin DuChang HuaWenjie LiHao ZhangXinru LiuYufeng WangChao JiangJiakun GuoQiang LvCraig S AndersonChunguang QiuChang Sheng MaPublished in: Circulation (2023)
Frailty status was a marker of high cardiovascular risk. Patients with frailty benefit similarly to other patients from intensive blood pressure control without an increased risk of serious adverse events.
Keyphrases
- blood pressure
- end stage renal disease
- community dwelling
- chronic kidney disease
- newly diagnosed
- hypertensive patients
- ejection fraction
- clinical trial
- heart rate
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- high intensity
- metabolic syndrome
- patient reported outcomes
- phase ii
- skeletal muscle
- patient reported