Docetaxel Targets Aggressive Methylation Profiles and Serves as a Radiosensitizer in High-Risk Meningiomas.

Mark W YoungbloodAnh N TranWenxia WangShejuan AnDenise ScholtensLyndsee ZhangKaitlyn O'SheaJenny L PokornyStephen T MagillSean SachdevRimas V LukasAtique U AhmedDusten UnruhJordain WalshonKathleen McCortneyYufen WangAneta BaranFelix Sahm Kenneth D AldapeJames P ChandlerC David JamesAmy B HeimbergerCraig M Horbinski

Published in: Neuro-oncology (2022)

Global patterns of DNA methylation may be informative for the selection of chemotherapies against meningiomas, and existing drugs may enhance radiation sensitivity in high-risk cases.

Keyphrases

dna methylation
genome wide
gene expression
squamous cell carcinoma
locally advanced
copy number
rectal cancer