Myositis Autoantigen Expression Correlates With Muscle Regeneration but Not Autoantibody Specificity.
Iago Pinal-FernandezDavid R AmiciCassie A ParksAssia DerfoulMaria Casal-DominguezKatherine PakRichard YekerPaul PlotzJose C MilisendaJosep M Grau-JunyentAlbert Selva-O'CallaghanJulie J PaikJemima AlbaydaAndrea M CorseThomas E LloydLisa Christopher-StineAndrew L MammenPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2019)
Most myositis autoantigens are highly expressed during muscle regeneration, which may relate to the propagation of autoimmunity. However, factors other than overexpression of specific autoantigens are likely to govern the development of unique autoantibodies in individual patients with myositis.