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Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction.

Giovanni CoticchioAmy BarrieCristina LagallaAntonio MonacoSimon FishelDarren K GriffinAlison Campbell
Published in: Human reproduction update (2022)
Deviations from developmental dogmas and the increasing evidence of plasticity of the human embryo challenge current embryological notions and suggest the need to write new rules governing cell cycle, cell determination and chromosome segregation during preimplantation development.
Keyphrases
  • cell cycle
  • endothelial cells
  • cell proliferation
  • pluripotent stem cells
  • single cell
  • stem cells
  • gene expression
  • mass spectrometry
  • bone marrow
  • genome wide