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Dysphagia in Parkinson Disease: Part II-Current Treatment Options and Insights from Animal Research.

Maryann N KraskoDenis Michael RudischRyan J BurdickNicole E Schaen-HeacockCourtney K BroadfootAlex F NisbetNicole M Rogus-PuliaMichelle R Ciucci
Published in: Current physical medicine and rehabilitation reports (2023)
Dysphagia is an early, common, and debilitating sign of PD. Current pharmacological and surgical interventions are not effective in ameliorating swallowing dysfunction; behavioral intervention remains the most effective approach for dysphagia treatment. Animal research has advanced our understanding of mechanisms underlying PD and PD-associated dysphagia, and continues to show translational promise for the study of dysphagia treatment options.
Keyphrases
  • parkinson disease
  • deep brain stimulation
  • randomized controlled trial
  • oxidative stress
  • big data