A retrospective case control study identifies peripheral blood mononuclear cell albumin RNA expression as a biomarker for non-alcoholic fatty liver disease.
Xin ChuKelsey KarasinskiSean DonellanScott KaniperG Craig WoodWeixing ShiMichael A EdwardsRohit SoansChristopher D StillGlenn S GerhardPublished in: Langenbeck's archives of surgery (2019)
Albumin RNA expression from blood cells may serve as a biomarker of NAFLD. Albumin and alpha fetoprotein appear to be ubiquitously expressed in visceral adipose tissue in patients with extreme obesity.
Keyphrases
- peripheral blood
- insulin resistance
- adipose tissue
- poor prognosis
- induced apoptosis
- metabolic syndrome
- type diabetes
- weight loss
- single cell
- binding protein
- cell cycle arrest
- high fat diet
- genome wide
- gene expression
- weight gain
- stem cells
- skeletal muscle
- endoplasmic reticulum stress
- body mass index
- dna methylation
- oxidative stress
- cell death
- mesenchymal stem cells
- pi k akt