Fatty Acid Synthase Inhibitor TVB-2640 Reduces Hepatic de Novo Lipogenesis in Males With Metabolic Abnormalities.
Majid Mufaqam Syed-AbdulElizabeth J ParksAyman H GaballahKimberlee BinghamGhassan M HammoudGeorge KembleDouglas BuckleyWilliam McCullochCamila Manrique-AcevedoPublished in: Hepatology (Baltimore, Md.) (2020)
These data support the therapeutic potential of a fatty acid synthase inhibitor, TVB-2640 in particular, in patients with NAFLD and nonalcoholic steatohepatitis.