The pharmacological management of acute behavioural disturbance: Data from a clinical audit conducted in UK mental health services.
Carol PatonClive E AdamsStephen DyeElizabeth FaganChike OkochaThomas Re BarnesPublished in: Journal of psychopharmacology (Oxford, England) (2018)
The current management of acutely disturbed behaviour with parenteral medication may fail to achieve a calming effect in up to a quarter of episodes. The most common rapid tranquillisation combination used was lorazepam and haloperidol, for which the randomised controlled trial evidence is very limited. Rapid tranquillisation prescribing practice was not wholly consistent with the relevant National Institute for Health and Care Excellence guideline, which recommends intramuscular lorazepam on its own or intramuscular haloperidol combined with intramuscular promethazine. Clinical factors prompting the use of rapid tranquillisation rather than oral medication may differ between the genders.
Keyphrases
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- adverse drug
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- mental health
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