Androgens stimulate erythropoiesis through the DNA-binding activity of the androgen receptor in non-hematopoietic cells.

Julie F McManusNhu-Y N NguyenRachel A DaveyHelen E MacLeanGiovanna PomilioMatthew P McCormackWan Sze ChiuAndrew H WeiJeffrey D ZajacDavid J Curtis

Published in: European journal of haematology (2020)

Erythroid promoting effects of androgens are mediated through DNA binding-dependent actions of the AR in non-hematopoietic cells, including stimulating EPO expression.

Keyphrases

dna binding
induced apoptosis
transcription factor
cell cycle arrest
bone marrow
poor prognosis
signaling pathway
cell death
cell proliferation
binding protein
long non coding rna