Androgens stimulate erythropoiesis through the DNA-binding activity of the androgen receptor in non-hematopoietic cells.
Julie F McManusNhu-Y N NguyenRachel A DaveyHelen E MacLeanGiovanna PomilioMatthew P McCormackWan Sze ChiuAndrew H WeiJeffrey D ZajacDavid J CurtisPublished in: European journal of haematology (2020)
Erythroid promoting effects of androgens are mediated through DNA binding-dependent actions of the AR in non-hematopoietic cells, including stimulating EPO expression.