Longitudinal Changes in Hippocampal Network Connectivity in Alzheimer's Disease.
Sophie DautricourtRobin de FloresBrigitte LandeauGéraldine PoisnelMatthieu VanhoutteNicolas DelcroixFrancis EustacheDenis VivienVincent de la SayetteGaëlle ChételatPublished in: Annals of neurology (2021)
Our findings demonstrate that longitudinal connectivity changes in the posterior-medial and anterior-temporal hippocampal networks are linked together and that they both contribute to cognitive decline in Alzheimer's disease. These results shed light on the critical role of the posterior-medial and anterior-temporal networks in Alzheimer's disease pathophysiology and clinical symptoms. ANN NEUROL 2021;90:391-406.