Epigenetic Regulation Interplays with Endometriosis Pathogenesis in Low-Birth-Weight Patients via the Progesterone Receptor B-VEGF-DNMT1 Axis.
Arief SetiawanRuswana AnwarMas Rizky Anggun Adipurna SyamsunarnoJohanes Cornelius MoseBudi SantosoAni Melani MaskoenWiryawan PermadiBudi SetiabudiawanMeita DhamayantiYudi Mulyana HidayatPublished in: Diagnostics (Basel, Switzerland) (2023)
Endometriosis is associated with PR-B gene promoter hypermethylation, decreased PR-B expression, and increased DNMT1 and VEGF expression. The methylation of PR-B is the most dominant factor affecting endometriosis incidence.
Keyphrases
- dna methylation
- low birth weight
- poor prognosis
- end stage renal disease
- genome wide
- preterm infants
- vascular endothelial growth factor
- endothelial cells
- ejection fraction
- newly diagnosed
- chronic kidney disease
- binding protein
- gene expression
- peritoneal dialysis
- prognostic factors
- risk factors
- copy number
- patient reported outcomes