Women with Low-Risk DCIS Eligible for the LORIS Trial After Complete Surgical Excision: How Low Is Their Risk After Standard Therapy?
Melissa PilewskieCristina OlceseSujata PatilKimberly J VanZeePublished in: Annals of surgical oncology (2016)
Women meeting LORIS criteria (after complete surgical excision) are at somewhat lower risk for IBTR. Among such women undergoing excision without RT, the 10-year invasive-IBTR rate was 6 %. Given that approximately 20 % of women with core biopsy-proven non-high-grade DCIS have invasive cancer at excision, women managed without excision would be expected to incur higher invasive cancer rates. Additional criteria are needed to identify women not requiring intervention for DCIS.
Keyphrases
- polycystic ovary syndrome
- high grade
- pregnancy outcomes
- papillary thyroid
- breast cancer risk
- cervical cancer screening
- randomized controlled trial
- clinical trial
- stem cells
- squamous cell
- adipose tissue
- pregnant women
- study protocol
- type diabetes
- metabolic syndrome
- mesenchymal stem cells
- low grade
- lymph node metastasis
- replacement therapy