Development of fatty acid metabolism score based on gene signature for predicting prognosis and immunotherapy response in colon cancer.

Changchun YeQi SunJun YanDong XueJiarui XuHaiyun MaFanni Li

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2023)

Our study provided a comprehensive analysis of the heterogeneity of fatty acid metabolism in colon cancer. We highlighted the potential clinical utility of fatty acid metabolism-related genes to be biomarkers of colon cancer prognosis and targets to improve the effect of immunotherapy.

Keyphrases

fatty acid
genome wide
copy number
gene expression
risk assessment
transcription factor