Atrophy of calf muscles by unloading results in an increase of tissue sodium concentration and fat fraction decrease: a 23Na MRI physiology study.
Darius A GerlachK SchopenP LinzB JohannesJ TitzeJ ZangeJ RittwegerPublished in: European journal of applied physiology (2017)
Unloading atrophy is associated with an increase in muscle sodium concentration. 23Na MRI is capable of detecting these rather small changes.