Exercise Rehabilitation and Chronic Respiratory Diseases: Effects, Mechanisms, and Therapeutic Benefits.
Ting XiongXinyue BaiXingyi WeiLezheng WangFei LiHui ShiYue ShiPublished in: International journal of chronic obstructive pulmonary disease (2023)
Chronic respiratory diseases (CRD), is a group of disorders, primarily chronic obstructive pulmonary disease and asthma, which are characterized by high prevalence and disability, recurrent acute exacerbations, and multiple comorbidities, resulting in exercise limitations and reduced health-related quality of life. Exercise training, an important tool in pulmonary rehabilitation, reduces adverse symptoms in patients by relieving respiratory limitations, increasing gas exchange, increasing central and peripheral hemodynamic forces, and enhancing skeletal muscle function. Aerobic, resistance, and high-intensity intermittent exercises, and other emerging forms such as aquatic exercise and Tai Chi effectively improve exercise capacity, physical fitness, and pulmonary function in patients with CRD. The underlying mechanisms include enhancement of the body's immune response, better control of the inflammatory response, and acceleration of the interaction between the vagus and sympathetic nerves to improve gas exchange. Here, we reviewed the new evidence of benefits and mechanisms of exercise intervention in the pulmonary rehabilitation of patients with chronic obstructive pulmonary disease, bronchial asthma, bronchiectasis, interstitial lung disease, and lung cancer.
Keyphrases
- high intensity
- chronic obstructive pulmonary disease
- resistance training
- skeletal muscle
- interstitial lung disease
- immune response
- inflammatory response
- lung function
- systemic sclerosis
- randomized controlled trial
- cystic fibrosis
- pulmonary hypertension
- end stage renal disease
- risk assessment
- newly diagnosed
- respiratory tract
- type diabetes
- room temperature
- drug induced
- rheumatoid arthritis
- prognostic factors
- chronic kidney disease
- body composition
- insulin resistance
- liver failure
- emergency department
- dendritic cells
- allergic rhinitis
- hepatitis b virus
- extracorporeal membrane oxygenation
- electronic health record
- aortic dissection
- metabolic syndrome
- lps induced