New Updates of the Imaging Role in Diagnosis, Staging, and Response Treatment of Malignant Pleural Mesothelioma.
Chiara RomeiSalvatore Claudio FanniFederica VolpiAlessio MilazzoCaterina Aida D'AmoreLeonardo ColligianiEmanuele NeriAnnalisa De LiperiGiulia Maria StellaChandra BortolottoPublished in: Cancers (2021)
Malignant pleural mesothelioma is a rare neoplasm with poor prognosis. CT is the first imaging technique used for diagnosis, staging, and assessment of therapy response. Although, CT has intrinsic limitations due to low soft tissue contrast and the current staging system as well as criteria for evaluating response, it does not consider the complex growth pattern of this tumor. Computer-based methods have proven their potentiality in diagnosis, staging, prognosis, and assessment of therapy response; moreover, computer-based methods can make feasible tasks like segmentation that would otherwise be impracticable. MRI, thanks to its high soft tissue contrast evaluation of contrast enhancement and through diffusion-weighted-images, could replace CT in many clinical settings.
Keyphrases
- contrast enhanced
- diffusion weighted
- poor prognosis
- magnetic resonance imaging
- magnetic resonance
- lymph node
- computed tomography
- soft tissue
- deep learning
- pet ct
- high resolution
- dual energy
- long non coding rna
- positron emission tomography
- low grade
- working memory
- mass spectrometry
- mesenchymal stem cells
- replacement therapy
- high grade