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Predictive factors for adnexal involvement in endometrial cancer FIGO stage IIIA.

Giorgia DinoiDomenica LorussoEleonora La FeraStefano RestainoPia Clara PafundiAlessandro GioèLaura NaccaratoEmilia PalmieriLucia MusacchioEttore Di StefanoVincenzo TarantinoGiovanni ScambiaFrancesco Fanfani
Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2024)
Our study showed that ovarian preservation may be considered for younger patients with low-risk endometrial cancer (G1 and G2 tumors, absence of lymphovascular space invasion, no cervical involvement, and myometrial invasion <50%), adding a favorable predictive role to higher body mass index and high β-catenin expression.
Keyphrases
  • endometrial cancer
  • cell migration
  • poor prognosis
  • epithelial mesenchymal transition
  • cell proliferation
  • signaling pathway