Combination treatment with hENT1 and miR-143 reverses gemcitabine resistance in triple-negative breast cancer.

Yue XiTing LiYun XiXinyi ZengYing MiaoRui GuoMin ZhangBiao Li

Published in: Cancer cell international (2022)

Combined therapy of exogenous upregulation of hENT1 expression and miR-143 mimic administration was effective in reversing GEM resistance, providing a promising strategy for treating GEM-resistant TNBC.

Keyphrases

cell proliferation
long non coding rna
poor prognosis
long noncoding rna
signaling pathway
stem cells
squamous cell carcinoma
binding protein
radiation therapy
combination therapy
locally advanced
replacement therapy