Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis.

Mei MaoWen FanYan ZhengPan QiMin XiYuanrong Yao

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

Silencing Cav2.2 expression can significantly reduce the clinical score, pathological injury, and mechanical allodynia, reducing the release of inflammatory factors, thus improving neuropathic pain in EAN rats.

Keyphrases

neuropathic pain
poor prognosis
spinal cord
spinal cord injury
long non coding rna
multiple sclerosis
oxidative stress
cell proliferation
signaling pathway
binding protein
drug induced
spectrum disorder