Feasibility and safety of radical prostatectomy for oligo-metastatic prostate cancer: TRoMbone trial.

Prasanna SooriakumaranCaroline WilsonInes RombachNeelam HassanaliJonathan AningAlastair D LambPaul CathcartChristopher EdenImran AhmadPrabhakar RajanAshwin SridharRichard John BryantOussama ElhageJonathan CookHing LeungNaeem SoomroJohn KellySenthil NathanJenny L DonovanFreddie C Hamdy

Published in: BJU international (2021)

It is feasible to randomise men with synchronous oligo-metastatic prostate cancer to a surgical intervention in addition to standard systemic therapies. While surgery appeared safe with no substantial impact on QOL in this feasibility study, a large randomised controlled trial is now warranted to examine treatment effectiveness of this additional component in the multi-modality management of oligo-metastatic prostate cancer.

Keyphrases

prostate cancer
radical prostatectomy
squamous cell carcinoma
small cell lung cancer
randomized controlled trial
study protocol
systematic review
clinical trial
coronary artery bypass
coronary artery disease
phase ii
double blind