MRP1 protein expression in leukemic stem cells as a negative prognostic marker in acute myeloid leukemia patients.

Maria PaprockaAleksandra Bielawska-PohlJoanna RossowskaAgnieszka KrawczenkoDanuta DuśMarek KiełbińskiOlga HausMaria Podolak-DawidziakKazimierz Kuliczkowski

Published in: European journal of haematology (2017)

Our data present for the very first time the high negative correlation between MRP1 protein expression in LSC and AML patients' remission. It does strongly suggest that MRP1 expression in LSC is an adverse prognostic marker in patients with de novo AML.

Keyphrases

stem cells
end stage renal disease
acute myeloid leukemia
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
poor prognosis
systemic lupus erythematosus
big data
cell therapy
acute lymphoblastic leukemia
disease activity
data analysis