Acute ischaemic stroke interventions: large vessel occlusion and beyond.
Ahmad SweidBatoul HammoudSunidhi RameshDaniella WongTyler D AlexanderJoshua Harrison WeinbergMaureen DeprinceJaime DoughertyDimitri Jean-Mickael MaamariStavropoula TjoumakarisHekmat ZarzourMichael R GoochNabeel HerialVictor RomoDavid M HasanRobert H RosenwasserPascal M JabbourPublished in: Stroke and vascular neurology (2019)
Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy. Large vessel occlusion (LVO) accounts for up to 38% of acute ischaemic stroke and comes with devastating outcomes for patients, families and society in the pre-intervention era. A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke; this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits. This review article will present a comprehensive overview of LVO management, techniques and devices used, and the future of stroke therapy. In addition, we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion.
Keyphrases
- liver failure
- respiratory failure
- drug induced
- aortic dissection
- randomized controlled trial
- healthcare
- end stage renal disease
- ejection fraction
- newly diagnosed
- stem cells
- atrial fibrillation
- type diabetes
- palliative care
- prognostic factors
- minimally invasive
- peritoneal dialysis
- mesenchymal stem cells
- extracorporeal membrane oxygenation
- quality improvement
- insulin resistance
- pain management
- replacement therapy