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Metabolites of 2- and 3-Monochloropropanediol (2- and 3-MCPD) in Humans: Urinary Excretion of 2-Chlorohydracrylic Acid and 3-Chlorolactic Acid after Controlled Exposure to a Single High Dose of Fatty Acid Esters of 2- and 3-MCPD.

Nick BergauZhiyong ZhaoKlaus AbrahamBernhard H Monien
Published in: Molecular nutrition & food research (2021)
The products of oxidative metabolism of 2- and 3-MCPD, 2-ClHA, and 3-ClLA, are described for the first time in humans. Due to the lack of specificity, the metabolites may not be used as exposure biomarkers to low doses of bound 2- and 3-MCPD, respectively.
Keyphrases
  • high dose
  • fatty acid
  • ms ms
  • low dose
  • stem cell transplantation
  • structural basis