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Prevalence of vitamin B-12 insufficiency during pregnancy and its effect on offspring birth weight: a systematic review and meta-analysis.

Nithya SukumarSnorri B RafnssonNgianga-Bakwin KandalaRaj BhopalChittaranjan S YajnikPonnusamy Saravanan
Published in: The American journal of clinical nutrition (2016)
Our review indicates that vitamin B-12 insufficiency during pregnancy is common even in nonvegetarian populations and that concentrations of vitamin B-12 decrease from the first to the third trimester. There is no consistent association between vitamin B-12 insufficiency and LBW. However, given the long-term risks of LBW, this observation warrants further cohort studies and randomized controlled trials.
Keyphrases
  • birth weight
  • gestational age
  • randomized controlled trial
  • weight gain
  • preterm birth
  • high fat diet
  • human health
  • systematic review
  • risk assessment
  • pregnant women
  • physical activity
  • study protocol