First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus.

Aspen M WorkmanMichael L ClawsonMichael P HeatonAaron M Dickey

Published in: Microbiology resource announcements (2018)

Genetic variation in the ovine TMEM154 gene associates with susceptibility to small ruminant lentivirus (SRLV) infection. We report here the first complete genome sequence for a genotype A2, subgroup 4 SRLV isolated from a Hampshire ewe with two copies of a TMEM154 frameshift mutation predicted to abolish protein function.

Keyphrases

genome wide
phase iii
amino acid
copy number
clinical trial
randomized controlled trial
protein protein
dna methylation
gene expression
small molecule