Expression of β1 adrenergic receptor in vascular anomalies in children.
Maria-Corina StănciulescuMarius-Călin PopoiuAnca Maria CîmpeanVlad Laurentiu DavidRodica HeredeaSimona CerbuEugen-Sorin BoiaPublished in: The Journal of international medical research (2021)
Our research demonstrates, for the first time, the degree of heterogeneous expression of β1-AR among pediatric vascular malformations. Our results support the need for β1-AR assessment in pediatric vascular anomalies to select cases with a robust response to β1-selective blockers. β1-AR assessment may have a strong impact on therapeutic refinement for pediatric vascular anomalies by selecting cases with a stronger response to beta-blockers.