Impact of amyloid and tau positivity on longitudinal brain atrophy in cognitively normal individuals.
Motonobu FujishimaYohei KawasakiToshiharu MitsuhashiHiroshi Matsudanull nullPublished in: Alzheimer's research & therapy (2024)
In cognitively normal individuals, A + T + compounds brain atrophy and cognitive deterioration, amplifying the likelihood of disease progression. Therapeutic interventions targeting A + T + individuals could be pivotal in curbing brain atrophy, cognitive decline, and disease progression.