A successful multidisciplinary approach for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia during pregnancy.
Mahmoud SalamaEvgenia IsachenkoSebastian LudwigThomas EinzmannGohar RahimiPeter MallmannVladimir IsachenkoPublished in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2018)
Leukemia in pregnancy is a rare condition with the prevalence of 1 in 75,000-100,000 pregnancies. In this case report, we present a successful multidisciplinary management strategy for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia (ALL) during pregnancy. Several complex challenges existed and necessitated a multidisciplinary approach with strong coordination and collaboration between oncologists, gynecologists, reproductive cryobiologists, obstetricians, and neonatologists in order to improve the maternal and fetal outcome. Pregnancy in the second trimester is neither a contraindication for ALL treatment nor for emergency fertility preservation via ovarian tissue extraction and further cryopreservation.
Keyphrases
- rare case
- pregnancy outcomes
- acute myeloid leukemia
- case report
- bone marrow
- emergency department
- public health
- healthcare
- quality improvement
- risk factors
- respiratory failure
- pregnant women
- risk assessment
- hepatitis b virus
- acute respiratory distress syndrome
- replacement therapy
- aortic dissection
- weight loss
- advanced cancer
- mechanical ventilation