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Additive interaction of mid- to late-life depression and cerebrovascular disease on the risk of dementia: a nationwide population-based cohort study.

Yoo Jin JangCinoo KangWoojae MyungShinn-Won LimYoung Kyung MoonHo KimDoh Kwan Kim
Published in: Alzheimer's research & therapy (2021)
In this population-based nationwide cohort with long-term follow-up, depression and CVD were associated with an increased risk of dementia, and their coexistence additively increased dementia risk more than the sum of the individual risks.
Keyphrases
  • mild cognitive impairment
  • cognitive impairment
  • depressive symptoms
  • sleep quality
  • cross sectional
  • human health
  • risk assessment
  • physical activity
  • climate change